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Not just about smoking: Lung cancer’s evolving face in the Americas

Lung cancer is often seen as a disease that only affects smokers, but the reality is far more complex. While tobacco use remains the primary cause, research shows that environmental exposures, genetics, and lifestyle factors can also significantly increase risk. November, Lung Cancer Awareness Month, is a timely reminder of the many causes and the urgent need for prevention, early detection, and public awareness across the Americas.

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Globally, lung cancer is one of the deadliest cancers, with nearly 2.5 million new cases reported in 2022. In the United States, more than 220,000 new cases are projected for 2025. In the Caribbean, accurate data are limited, but trends from the region and the Americas indicate a growing risk, particularly in areas with high smoking rates, urban air pollution, and limited screening services.

Tobacco use remains the dominant factor, contributing to roughly 80% of lung cancer cases. Both active smoking and exposure to second-hand smoke increase risk. In some Caribbean countries, nearly one in five men still smoke, creating a significant health burden.

Environmental exposures are also critical contributors. Prolonged exposure to air pollution, including fine particulate matter from traffic, industrial activity, or open burning, can damage lung tissue and increase cancer risk. Indoor air pollution from cooking fuels and poor ventilation is another factor, especially in rural or lower-income households.

Occupational hazards play a role as well. Workers in industries such as construction, mining, or tourism infrastructure can be exposed to asbestos, silica dust, or other carcinogenic substances. Over time, these exposures can significantly elevate the likelihood of developing lung cancer.

Genetic and biological factors are increasingly recognized. A subset of patients develop lung cancer without a history of smoking or environmental exposure, often due to inherited mutations or other genetic susceptibilities. Women appear to be disproportionately affected in this group, highlighting the disease’s evolving patterns.

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Lifestyle factors such as diet, physical activity, and coexisting conditions (like chronic respiratory disease) can also influence risk. Studies show that poor nutrition, obesity, and chronic inflammation can contribute to cancer development, emphasizing the need for holistic approaches to prevention.

Early detection remains the most effective strategy to reduce deaths. Screening programs using low-dose CT scans can identify lung cancer at a treatable stage, but such programs are limited in the Caribbean due to resource constraints. Awareness campaigns, particularly during November, are essential to encourage at-risk individuals to seek medical evaluation for persistent coughs, chest pain, breathlessness, or unexplained weight loss.

Preventing lung cancer requires a multi-pronged approach: robust tobacco control, reducing exposure to air pollution, improving occupational safety, promoting healthy lifestyles, and strengthening health systems to provide early diagnosis and care. Diaspora and regional organizations can support these efforts by funding awareness campaigns, providing expertise, and helping establish screening and treatment infrastructure.

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Lung cancer may be a silent killer, but it is not inevitable. Understanding the many causes—from tobacco and pollution to genetics and lifestyle—gives communities the power to reduce risk, catch the disease early, and save lives. November is the moment to spark action across the Caribbean, raising awareness, promoting prevention, and protecting future generations.

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